DemeTECH’s Polyglactin 910 suture is a synthetic absorbable, sterile, surgical suture composed of copolymers made from 90% glycolide and 10% L-lactide. Polyglactin 910 suture is available in violet or colorless from sizes: USP 8-0 to USP 2.
Polyglactin 910 meets all the requirements established by the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP) for Synthetic Absorbable Surgical Sutures (except for an occasional oversize in some gauges).
Polyglactin 910 Suture is indicated for use in general soft tissue approximation and/or ligation, including use in ophthalmic surgery but not for use in cardiovascular or neurological tissue.
A slight tissue inflammation may occur when Polyglactin 910 Sutures are placed in tissue, which is characteristic of foreign body response, which is followed by gradual encapsulation by connective tissue. After which absorption by hydrolysis begins, where the polymer degrades to glycolic acid, which is absorbed by the body.
Polyglactin 910 elicits a minimal acute inflammatory reaction in tissues, which is followed by gradual encapsulation of the suture by fibrous connective tissue.
Progressive loss of tensile strength and eventual absorption of Polyglactin 910 synthetic absorbable sutures occurs by means of hydrolysis, where the polymer degrades to either glycolic acid or glycolic and lactic acids which are subsequently absorbed and metabolized by the body.
Absorption begins as a loss of tensile strength without appreciable loss of mass.
Complete loss of original tensile strength is lost by 5 weeks post implantation. Absorption of Polyglactin 910 absorbable synthetic suture is essentially complete between 56 and 70 days.
DemeTECH’s Polyglactin 910 suture is a synthetic absorbable, sterile, surgical suture composed of copolymers made from 90% glycolide and 10% L-lactide.
The chemical formula of DemeTECH’s Polyglactin 910 is (C2H2O2)m(C3H4O2)n. Clinical trials have shown that after two weeks, approximately 75% of DemeTECH’s Polyglactin 910 initial strength remained. At four weeks, approximately 25% of DemeTECH’s Polyglactin 910 linear tensile strength remained.
DemeTECH’s Polyglactin 910 has found to be nonantigenic and eliciting only mild tissue reactivity during the absorption process. DemeTECH’s Polyglactin 910 sutures are available violet and colorless.
- Polyglactin 910 is coated in order to create a smoother synthetic absorbable suture that will pass through tissue readily.
Coated Polyglactin 910 sutures facilitate:
- Easy tissue passage
- Precise knot placement
- Smooth tie down
- A decreased tendency to irritate tissue
- Greater tensile strength
- A longer absorption period
- After 3 weeks post operation, in clinical trials, DemeTECH’s Polyglactin 910 sutures still maintain approximately 50% of their tensile strength.